Reactome | SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix)

Schema > Reaction > Entries

SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix) Show undefined attributes

catalystActivity	[CatalystActivity:11074196] calcium:sodium antiporter activity of SLC8B1 [mitochondrial inner membrane]
category	transition
compartment	[Compartment:70616] mitochondrial inner membrane
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11074198
displayName	SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix)
eventOf	[Pathway:R-SPO-8949215] Mitochondrial calcium ion transport - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8949688] SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix) - Homo sapiens
input	[SimpleEntity:R-ALL-8949220] Ca2+ [mitochondrial matrix] 3 × [SimpleEntity:R-ALL-2889072] Na+ [mitochondrial intermembrane space]
isInDisease	false
isInferred	true
maxDepth	1
name	SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix)
output	[SimpleEntity:R-ALL-8949232] Ca2+ [mitochondrial intermembrane space] 3 × [SimpleEntity:R-ALL-2889083] Na+ [mitochondrial matrix]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-8949688
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SPO-8949215] Mitochondrial calcium ion transport
(inferredTo)	[Reaction:R-HSA-8949688] SLC8B1 (NCLX) exchanges sodium (mitochondrial intermembrane space) for calcium (mitochondrial matrix)

Cite Us!