Reactome | METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8

Schema > Reaction > Entries

METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 Show undefined attributes

catalystActivity	[CatalystActivity:11073780] protein-lysine N-methyltransferase activity of METTL21A [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11073782
displayName	METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8
eventOf	[Pathway:R-SPO-8876725] Protein methylation - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:5618933] regulation of protein folding
inferredFrom	[Reaction:R-HSA-8932221] METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 - Homo sapiens
input	3 × [SimpleEntity:R-ALL-77087] AdoMet [nucleoplasm] [DefinedSet:R-SPO-5082380-5] Homologues of HSPA8 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8
output	3 × [SimpleEntity:R-ALL-77502] AdoHcy [nucleoplasm] [DefinedSet:R-SPO-8932217-5] Homologues of Me3K561-HSPA8 [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-8932221
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SPO-8876725] Protein methylation
(inferredTo)	[Reaction:R-HSA-8932221] METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8

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