Reactome | Addition of nucleotides 10 and 11 on the growing transcript: Third Transition

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Addition of nucleotides 10 and 11 on the growing transcript: Third Transition Show undefined attributes

catalystActivity	[CatalystActivity:11054945] DNA-directed RNA polymerase activity of RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11055184
displayName	Addition of nucleotides 10 and 11 on the growing transcript: Third Transition
eventOf	[Pathway:R-SPO-73776] RNA Polymerase II Promoter Escape - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SPO-111264] Addition of nucleotides between position +11 and +30 - Schizosaccharomyces pombe
inferredFrom	[Reaction:R-HSA-76576] Addition of nucleotides 10 and 11 on the growing transcript: Third Transition - Homo sapiens
input	2 × [SimpleEntity:R-ALL-9757634] NTP [nucleoplasm] [Complex:R-SPO-75882] pol II transcription complex containing 9 nucleotide long transcript [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Addition of nucleotides 10 and 11 on the growing transcript: Third Transition
output	[Complex:R-SPO-75902] pol II transcription complex containing 11 nucleotide long transcript [nucleoplasm] 2 × [SimpleEntity:R-ALL-113541] PPi [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-76576
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SPO-73776] RNA Polymerase II Promoter Escape
(precedingEvent)	[Reaction:R-SPO-111264] Addition of nucleotides between position +11 and +30
(inferredTo)	[Reaction:R-HSA-76576] Addition of nucleotides 10 and 11 on the growing transcript: Third Transition

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