Reactome | Switching of origins to a post-replicative state

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Switching of origins to a post-replicative state Show undefined attributes

compartment	[Compartment:7660] nucleoplasm [Compartment:70101] cytosol
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11078257
displayName	Switching of origins to a post-replicative state
eventOf	[Pathway:R-SPO-69239] Synthesis of DNA - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Pathway:R-SPO-69190] DNA strand elongation - Schizosaccharomyces pombe
hasDiagram	false
hasEHLD	false
hasEvent	[Pathway:R-SPO-68949] Orc1 removal from chromatin - Schizosaccharomyces pombe [Pathway:R-SPO-69017] CDK-mediated phosphorylation and removal of Cdc6 - Schizosaccharomyces pombe [Reaction:R-SPO-69019] Mcm4,6,7 trimer forms and associates with the replication fork - Schizosaccharomyces pombe
inferredFrom	[Pathway:R-HSA-69052] Switching of origins to a post-replicative state - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Switching of origins to a post-replicative state
precedingEvent	[Pathway:R-SPO-68952] DNA replication initiation - Schizosaccharomyces pombe
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-69052
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SPO-69239] Synthesis of DNA
(precedingEvent)	[Pathway:R-SPO-69190] DNA strand elongation
(inferredTo)	[Pathway:R-HSA-69052] Switching of origins to a post-replicative state

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