Reactome | LIPT1 transfers lipoyl group from lipoyl-GCSH to DBT/DLST

Schema > Reaction > Entries

LIPT1 transfers lipoyl group from lipoyl-GCSH to DBT/DLST Show undefined attributes

catalystActivity	[CatalystActivity:11069913] N-acyltransferase activity of LIPT1 [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11069915
displayName	LIPT1 transfers lipoyl group from lipoyl-GCSH to DBT/DLST
eventOf	[Pathway:R-SPO-9857492] Protein lipoylation - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SPO-6793590] LIPT2 transfers octanoyl group to GCSH - Schizosaccharomyces pombe
inferredFrom	[Reaction:R-HSA-6792572] LIPT1 transfers lipoyl group from lipoyl-GCSH to DBT/DLST - Homo sapiens
input	[EntityWithAccessionedSequence:R-SPO-6793611] gcv3 [mitochondrial matrix] [EntityWithAccessionedSequence:R-SPO-6792574] kgd2 [mitochondrial matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	LIPT1 transfers lipoyl group from lipoyl-GCSH to DBT/DLST
output	[EntityWithAccessionedSequence:R-SPO-5693951] gcv3 [mitochondrial matrix] [EntityWithAccessionedSequence:R-SPO-69993] kgd2 [mitochondrial matrix]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-6792572
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SPO-9857492] Protein lipoylation
(precedingEvent)	[Reaction:R-SPO-6793590] LIPT2 transfers octanoyl group to GCSH
(inferredTo)	[Reaction:R-HSA-6792572] LIPT1 transfers lipoyl group from lipoyl-GCSH to DBT/DLST

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