Reactome | USP43 binds ISG:K164,ISG:K168-PCNA

Schema > Reaction > Entries

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11067124
displayName	USP43 binds ISG:K164,ISG:K168-PCNA
eventOf	[Pathway:R-SPO-5656169] Termination of translesion DNA synthesis - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5653780] USP43 binds ISG:K164,ISG:K168-PCNA - Homo sapiens
input	[DefinedSet:R-SPO-5653784-4] Homologues of USP43 [nucleoplasm] [Complex:R-SPO-5653772] ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	USP43 binds ISG:K164,ISG:K168-PCNA
output	[Complex:R-SPO-5653781] USP43:ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-5653780
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SPO-5656169] Termination of translesion DNA synthesis
(inferredTo)	[Reaction:R-HSA-5653780] USP43 binds ISG:K164,ISG:K168-PCNA

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