Reactome | ATP2B4 binds to NOS1, inhibiting it

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11066762
displayName	ATP2B4 binds to NOS1, inhibiting it
eventOf	[Pathway:R-SPO-5578775] Ion homeostasis - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5617178] ATP2B4 binds to NOS1, inhibiting it - Homo sapiens
input	[EntityWithAccessionedSequence:R-SPO-418304] ATP2B4 [plasma membrane] [EntityWithAccessionedSequence:R-SPO-419293] NOS1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	ATP2B4 binds to NOS1, inhibiting it
output	[Complex:R-SPO-5617181] ATP2B4:NOS1 [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-5617178
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SPO-5578775] Ion homeostasis
(inferredTo)	[Reaction:R-HSA-5617178] ATP2B4 binds to NOS1, inhibiting it

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