Reactome | Glyoxylate metabolism and glycine degradation

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Glyoxylate metabolism and glycine degradation Show undefined attributes

created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11079067
displayName	Glyoxylate metabolism and glycine degradation
eventOf	[Pathway:R-SPO-71291] Metabolism of amino acids and derivatives - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:537] carboxylic acid metabolic process
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-SPO-6784224] PRODH2:FAD dimer dehydrogenates HPRO to 1-pyrroline-3-hydroxy-5-carboxylate - Schizosaccharomyces pombe [Reaction:R-SPO-6784393] PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) - Schizosaccharomyces pombe [Reaction:R-SPO-389821] glycine + O2 => glyoxylate + H2O2 + NH4+ - Schizosaccharomyces pombe [Reaction:R-SPO-6810076] DDO oxidizes D-Asp to OA - Schizosaccharomyces pombe [Pathway:R-SPO-6783984] Glycine degradation - Schizosaccharomyces pombe
inferredFrom	[Pathway:R-HSA-389661] Glyoxylate metabolism and glycine degradation - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Glyoxylate metabolism and glycine degradation
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-389661
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SPO-71291] Metabolism of amino acids and derivatives
(hasEncapsulatedEvent)	[Pathway:R-SPO-70268] Pyruvate metabolism [Pathway:R-SPO-9857492] Protein lipoylation
(inferredTo)	[Pathway:R-HSA-389661] Glyoxylate metabolism and glycine degradation

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