Reactome | Antizyme OAZ binds to Ornithine decarboxylase

Schema > Reaction > Entries

Antizyme OAZ binds to Ornithine decarboxylase Show undefined attributes

catalystActivity	[CatalystActivity:11059145] ornithine decarboxylase inhibitor activity of OAZ [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11059149
displayName	Antizyme OAZ binds to Ornithine decarboxylase
eventOf	[Pathway:R-SPO-350562] Regulation of ornithine decarboxylase (ODC) - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-SPO-353125] 26S proteosome degrades ODC holoenzyme complex - Schizosaccharomyces pombe
inferredFrom	[Reaction:R-HSA-350567] Antizyme OAZ binds to Ornithine decarboxylase - Homo sapiens
input	[EntityWithAccessionedSequence:R-SPO-70689] PXLP-K69-ODC1 [cytosol] [EntityWithAccessionedSequence:R-SPO-350587] spa1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Antizyme OAZ binds to Ornithine decarboxylase
output	[Complex:R-SPO-353118] ODC:OAZ complex [cytosol]
precedingEvent	[BlackBoxEvent:R-SPO-353125] 26S proteosome degrades ODC holoenzyme complex - Schizosaccharomyces pombe
regulatedBy	[NegativeRegulation:11059150] Negative regulation by 'AZIN1 [cytosol]'
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-350567
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SPO-350562] Regulation of ornithine decarboxylase (ODC)
(precedingEvent)	[BlackBoxEvent:R-SPO-353125] 26S proteosome degrades ODC holoenzyme complex
(inferredTo)	[Reaction:R-HSA-350567] Antizyme OAZ binds to Ornithine decarboxylase

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