Reactome | SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix)

Schema > Reaction > Entries

SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) Show undefined attributes

catalystActivity	[CatalystActivity:11064868] superoxide dismutase activity of SOD2 tetramer [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11064870
displayName	SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix)
eventOf	[Pathway:R-SPO-3299685] Detoxification of Reactive Oxygen Species - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-3299680] SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix) - Homo sapiens
input	2 × [SimpleEntity:R-ALL-113529] H+ [mitochondrial matrix] 2 × [SimpleEntity:R-ALL-3299683] O2.- [mitochondrial matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix)
output	[SimpleEntity:R-ALL-1614617] H2O2 [mitochondrial matrix] [SimpleEntity:R-ALL-113533] O2 [mitochondrial matrix]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-3299680
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SPO-3299685] Detoxification of Reactive Oxygen Species
(inferredTo)	[Reaction:R-HSA-3299680] SOD2 catalyzes 2H+ + 2O2.- => O2 + H2O2 (mitochondrial matrix)

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