Reactome | COQ5 methylates MDMQ10H2

Schema > Reaction > Entries

COQ5 methylates MDMQ10H2 Show undefined attributes

catalystActivity	[CatalystActivity:11063829] 2-methoxy-6-polyprenyl-1,4-benzoquinol methyltransferase activity of COQ3:COQ4:COQ5:COQ6:COQ7:COQ9 [mitochondrial inner membrane]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11063831
displayName	COQ5 methylates MDMQ10H2
eventOf	[Pathway:R-SPO-2142789] Ubiquinol biosynthesis - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SPO-2162194] COQ7:COQ9 octamer hydroxylates DMQ10H2 - Schizosaccharomyces pombe
inferredFrom	[Reaction:R-HSA-2162188] COQ5 methylates MDMQ10H2 - Homo sapiens
input	[SimpleEntity:R-ALL-2162265] AdoMet [mitochondrial matrix] [SimpleEntity:R-ALL-2162205] MDMQ10H2 [mitochondrial inner membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	COQ5 methylates MDMQ10H2 MDMQ10H2 is methylated to DMQ10H2 by COQ5
output	[SimpleEntity:R-ALL-2162252] AdoHcy [mitochondrial matrix] [SimpleEntity:R-ALL-2162204] DMQ10H2 [mitochondrial inner membrane] [SimpleEntity:R-ALL-113529] H+ [mitochondrial matrix]
precedingEvent	[Reaction:R-SPO-8855062] SLC25A26 exchanges cytosolic AdoMet for mitochondrial AdoHcy - Schizosaccharomyces pombe
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-2162188
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SPO-2142789] Ubiquinol biosynthesis
(precedingEvent)	[Reaction:R-SPO-2162194] COQ7:COQ9 octamer hydroxylates DMQ10H2
(inferredTo)	[Reaction:R-HSA-2162188] COQ5 methylates MDMQ10H2