Reactome | DLCL is acylated to MLCL by LCLAT1 (ER)

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DLCL is acylated to MLCL by LCLAT1 (ER) Show undefined attributes

catalystActivity	[CatalystActivity:11062749] O-acyltransferase activity of LCLAT1 [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11062756
displayName	DLCL is acylated to MLCL by LCLAT1 (ER)
eventOf	[Pathway:R-SPO-1482798] Acyl chain remodeling of CL - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SPO-1482861] MLCL is acylated to CL by LCLAT1 (ER) - Schizosaccharomyces pombe
inferredFrom	[Reaction:R-HSA-1482867] DLCL is acylated to MLCL by LCLAT1 (ER) - Homo sapiens
input	[SimpleEntity:R-ALL-1500578] acyl-CoA [cytosol] [SimpleEntity:R-ALL-1524080] DLCL [endoplasmic reticulum membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	DLCL is acylated to MLCL by LCLAT1 (ER)
output	[SimpleEntity:R-ALL-76194] CoA-SH [cytosol] [SimpleEntity:R-ALL-1524069] MLCL [endoplasmic reticulum membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-1482867
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SPO-1482798] Acyl chain remodeling of CL
(precedingEvent)	[Reaction:R-SPO-1482861] MLCL is acylated to CL by LCLAT1 (ER)
(inferredTo)	[Reaction:R-HSA-1482867] DLCL is acylated to MLCL by LCLAT1 (ER)

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