Reactome | 2-acyl LPE is acylated to PE by LPEAT

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2-acyl LPE is acylated to PE by LPEAT Show undefined attributes

catalystActivity	[CatalystActivity:11062639] 2-acylglycerol-3-phosphate O-acyltransferase activity of LPEAT [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
dbId	11062641
displayName	2-acyl LPE is acylated to PE by LPEAT
eventOf	[Pathway:R-SPO-1482839] Acyl chain remodelling of PE - Schizosaccharomyces pombe
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SPO-1482828] PE is hydrolyzed to 2-acyl LPE by PLA2[4] - Schizosaccharomyces pombe [Reaction:R-SPO-1483174] PE is methylated to PC by PEMT - Schizosaccharomyces pombe [Reaction:R-SPO-1482884] PE is hydrolyzed to 1-acyl LPE by PLA2[2] - Schizosaccharomyces pombe [Reaction:R-SPO-1482892] PE is hydrolyzed to 2-acyl LPE by PLA2G4C - Schizosaccharomyces pombe
inferredFrom	[Reaction:R-HSA-1482646] 2-acyl LPE is acylated to PE by LPEAT - Homo sapiens
input	[SimpleEntity:R-ALL-1498729] 2-acyl LPE [endoplasmic reticulum membrane] [SimpleEntity:R-ALL-1500578] acyl-CoA [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	2-acyl LPE is acylated to PE by LPEAT
output	[SimpleEntity:R-ALL-76194] CoA-SH [cytosol] [SimpleEntity:R-ALL-1500581] PE [endoplasmic reticulum membrane]
precedingEvent	[Reaction:R-SPO-1482828] PE is hydrolyzed to 2-acyl LPE by PLA2[4] - Schizosaccharomyces pombe [Reaction:R-SPO-1482892] PE is hydrolyzed to 2-acyl LPE by PLA2G4C - Schizosaccharomyces pombe
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68324] Schizosaccharomyces pombe
stId	R-SPO-1482646
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(precedingEvent)	[Reaction:R-SPO-1483174] PE is methylated to PC by PEMT [Reaction:R-SPO-1482884] PE is hydrolyzed to 1-acyl LPE by PLA2[2] [Reaction:R-SPO-1482828] PE is hydrolyzed to 2-acyl LPE by PLA2[4] [Reaction:R-SPO-1482892] PE is hydrolyzed to 2-acyl LPE by PLA2G4C
(hasEvent)	[Pathway:R-SPO-1482839] Acyl chain remodelling of PE
(inferredTo)	[Reaction:R-HSA-1482646] 2-acyl LPE is acylated to PE by LPEAT