Reactome | SPO11 Covalently Attached to Double-strand Break [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[BlackBoxEvent:R-SCE-981784] Removal of SPO11 and Resection of 5' Ends of DNA (yeast) - Saccharomyces cerevisiae
created	[InstanceEdit:981777] May, B, 2010-10-27
dbId	981780
displayName	SPO11 Covalently Attached to Double-strand Break [nucleoplasm]
hasComponent	2 × [OtherEntity:R-ALL-75165] DNA double-strand break ends [nucleoplasm] [Complex:R-SCE-981779] SPO11 Dimer (yeast) [nucleoplasm]
inDisease	false
isChimeric	false
literatureReference	[LiteratureReference:981735] Meiosis-specific DNA double-strand breaks are catalyzed by Spo11, a member of a widely conserved protein family [LiteratureReference:981762] Processing of meiotic DNA double strand breaks requires cyclin-dependent kinase and multiple nucleases [LiteratureReference:981741] Functional interactions between Sae2 and the Mre11 complex
maxDepth	3
modified	[InstanceEdit:5255525] May, B, 2014-02-06
name	SPO11 Covalently Attached to Double-strand Break SPO11:double-strand break
schemaClass	Complex
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-981780
updateTrackers	[UpdateTracker:9888787] Update Tracker - [Complex:981780] SPO11 Covalently Attached to Double-strand Break [nucleoplasm] - v48:[addName]

(updatedInstance)	[UpdateTracker:9888787] Update Tracker - [Complex:981780] SPO11 Covalently Attached to Double-strand Break [nucleoplasm] - v48:[addName]
(input)	[BlackBoxEvent:R-SCE-981784] Removal of SPO11 and Resection of 5' Ends of DNA (yeast)

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