Reactome | Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Schema > Pathway > Entries

Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Show undefined attributes

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11107600
displayName	Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
eventOf	[Pathway:R-SCE-927802] Nonsense-Mediated Decay (NMD) - Saccharomyces cerevisiae
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-SCE-927889] SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) - Saccharomyces cerevisiae [BlackBoxEvent:R-SCE-927836] SMG6 hydrolyzes mRNA with premature termination codon - Saccharomyces cerevisiae [BlackBoxEvent:R-SCE-927830] Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex - Saccharomyces cerevisiae
inferredFrom	[Pathway:R-HSA-975957] Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-975957
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SCE-927802] Nonsense-Mediated Decay (NMD)
(inferredTo)	[Pathway:R-HSA-975957] Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

© 2026 Reactome

Cite Us!