Reactome | SLC29A1 transports RBV from extracellular region to cytosol

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SLC29A1 transports RBV from extracellular region to cytosol Show undefined attributes

catalystActivity	[CatalystActivity:11083895] nucleoside transmembrane transporter activity of SLC29A1-like proteins [plasma membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11105228
displayName	SLC29A1 transports RBV from extracellular region to cytosol
eventOf	[Pathway:R-SCE-9755088] Ribavirin ADME - Saccharomyces cerevisiae
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SCE-9754929] SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix - Saccharomyces cerevisiae [Reaction:R-SCE-9755044] PNP trimer transforms RBV to T-CONH2 - Saccharomyces cerevisiae
inferredFrom	[Reaction:R-HSA-9755015] SLC29A1 transports RBV from extracellular region to cytosol - Homo sapiens
input	[ChemicalDrug:R-ALL-9755082] RBV [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	SLC29A1 transports RBV from extracellular region to cytosol SLC29A1 imports RBV
output	[ChemicalDrug:R-ALL-9680963] RBV [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-9755015
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SCE-9755088] Ribavirin ADME
(precedingEvent)	[Reaction:R-SCE-9754929] SLC29A3 transports RBV,RBV-TP from cytosol to mitochondrial matrix [Reaction:R-SCE-9755044] PNP trimer transforms RBV to T-CONH2
(inferredTo)	[Reaction:R-HSA-9755015] SLC29A1 transports RBV from extracellular region to cytosol

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