Reactome | Paracetamol ADME

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Paracetamol ADME Show undefined attributes

created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11108244
displayName	Paracetamol ADME
eventOf	[TopLevelPathway:R-SCE-9748784] Drug ADME - Saccharomyces cerevisiae
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:8764] xenobiotic metabolic process
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-SCE-9753278] ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 - Saccharomyces cerevisiae [Reaction:R-SCE-9753283] ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 - Saccharomyces cerevisiae [Reaction:R-SCE-9753634] GGT dimers hydrolyse APAP-SG - Saccharomyces cerevisiae [Reaction:R-SCE-9753632] CNDP2:2Mn2+ dimer hydrolyses APAP-CysGly - Saccharomyces cerevisiae [Reaction:R-SCE-9753284] ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region - Saccharomyces cerevisiae
inferredFrom	[Pathway:R-HSA-9753281] Paracetamol ADME - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Paracetamol ADME Acetaminophen ADME APAP ADME
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-9753281
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[TopLevelPathway:R-SCE-9748784] Drug ADME
(inferredTo)	[Pathway:R-HSA-9753281] Paracetamol ADME

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