Reactome | p-T1218, Y220 MAPK7 dimer [nucleoplasm]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:11086277] protein serine/threonine kinase activity of p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-SCE-203797] ERKs are inactivated by dual-specific phosphatases (DUSPs) - Saccharomyces cerevisiae [Reaction:R-SCE-199959] ERKs are inactivated by protein phosphatase 2A - Saccharomyces cerevisiae
created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11086276
displayName	p-T1218, Y220 MAPK7 dimer [nucleoplasm]
hasComponent	2 × [EntityWithAccessionedSequence:R-SCE-198738] phospho-p-T218,Y221-MAPK7 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-9610768] p-T1218, Y220 MAPK7 dimer [nucleoplasm] - Homo sapiens [DefinedSet:R-HSA-199878] p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] - Homo sapiens
maxDepth	2
name	p-T1218, Y220 MAPK7 dimer
schemaClass	Complex
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-9610768
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-SCE-203797] ERKs are inactivated by dual-specific phosphatases (DUSPs) [Reaction:R-SCE-199959] ERKs are inactivated by protein phosphatase 2A
(physicalEntity)	[CatalystActivity:11086277] protein serine/threonine kinase activity of p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm]
(inferredTo)	[DefinedSet:R-HSA-199878] p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] [Complex:R-HSA-9610768] p-T1218, Y220 MAPK7 dimer [nucleoplasm]