Reactome | TBC1D25 (OATL1) binds ATG8 homologues

Schema > Reaction > Entries

category	binding
compartment	[Compartment:5683628] autophagosome membrane [Compartment:5683636] autophagosome
created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11101859
displayName	TBC1D25 (OATL1) binds ATG8 homologues
eventOf	[Pathway:R-SCE-8854214] TBC/RABGAPs - Saccharomyces cerevisiae
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8854588] TBC1D25 (OATL1) binds ATG8 homologues - Homo sapiens
input	[EntityWithAccessionedSequence:R-SCE-5683634] ATG8 [autophagosome membrane] [EntityWithAccessionedSequence:R-SCE-8854607] GYP7 [autophagosome]
isInDisease	false
isInferred	true
maxDepth	1
name	TBC1D25 (OATL1) binds ATG8 homologues
output	[Complex:R-SCE-8854597] TBC1D25:ATG8 homoogues [autophagosome membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-8854588
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SCE-8854214] TBC/RABGAPs
(inferredTo)	[Reaction:R-HSA-8854588] TBC1D25 (OATL1) binds ATG8 homologues

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