Reactome | Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme

Schema > Reaction > Entries

Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme Show undefined attributes

catalystActivity	[CatalystActivity:11083771] polynucleotide 5'-phosphatase activity of Capping complex (initial) [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11083773
displayName	Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme
eventOf	[Pathway:R-SCE-72086] mRNA Capping - Saccharomyces cerevisiae
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SCE-77081] Formation of the CE:GMP intermediate complex - Saccharomyces cerevisiae
inferredFrom	[Reaction:R-HSA-77078] Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme - Homo sapiens
input	[Complex:R-SCE-77063] Capping complex (initial) [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme
output	[Complex:R-SCE-77064] Capping complex (hydrolyzed) [nucleoplasm] [SimpleEntity:R-ALL-113550] Pi [nucleoplasm]
precedingEvent	[Reaction:R-SCE-77077] Capping complex formation - Saccharomyces cerevisiae
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-77078
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SCE-72086] mRNA Capping
(precedingEvent)	[Reaction:R-SCE-77081] Formation of the CE:GMP intermediate complex
(inferredTo)	[Reaction:R-HSA-77078] Hydrolysis of the 5'-end of the nascent transcript by the capping enzyme

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