Reactome | Polymerase switching

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Polymerase switching Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11106650
displayName	Polymerase switching
eventOf	[Pathway:R-SCE-69109] Leading Strand Synthesis - Saccharomyces cerevisiae
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Pathway:R-SCE-69183] Processive synthesis on the lagging strand - Saccharomyces cerevisiae
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-SCE-69053] RFC binding displaces Pol Alpha - Saccharomyces cerevisiae [Reaction:R-SCE-69063] Loading of PCNA - Sliding Clamp Formation - Saccharomyces cerevisiae [Reaction:R-SCE-69068] RFC dissociates after sliding clamp formation - Saccharomyces cerevisiae
inferredFrom	[Pathway:R-HSA-69091] Polymerase switching - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Polymerase switching
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-69091
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SCE-69109] Leading Strand Synthesis [Pathway:R-SCE-69186] Lagging Strand Synthesis
(precedingEvent)	[Pathway:R-SCE-69183] Processive synthesis on the lagging strand
(inferredTo)	[Pathway:R-HSA-69091] Polymerase switching