Reactome | ALDH1A1 oxidises GA to DGA

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ALDH1A1 oxidises GA to DGA Show undefined attributes

catalystActivity	[CatalystActivity:11081829] aldehyde dehydrogenase (NAD+) activity of ALDH1A1 tetramer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11101358
displayName	ALDH1A1 oxidises GA to DGA
eventOf	[Pathway:R-SCE-70350] Fructose catabolism - Saccharomyces cerevisiae
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-6813749] ALDH1A1 oxidises GA to DGA - Homo sapiens
input	[SimpleEntity:R-ALL-30393] GA [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-29360] NAD+ [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	ALDH1A1 oxidises GA to DGA D-glyceraldehyde + H2O + NAD(+) => (R)-glycerate + 2 H(+) + NADH
output	[SimpleEntity:R-ALL-6799497] DGA [cytosol] 2 × [SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-73473] NADH [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-6813749
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SCE-70350] Fructose catabolism
(inferredTo)	[Reaction:R-HSA-6813749] ALDH1A1 oxidises GA to DGA

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