Reactome | COPI vesicle uncoating at the ER

Schema > BlackBoxEvent > Entries

COPI vesicle uncoating at the ER Show undefined attributes

category	omitted
compartment	[Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11101270
displayName	COPI vesicle uncoating at the ER
eventOf	[Pathway:R-SCE-6811434] COPI-dependent Golgi-to-ER retrograde traffic - Saccharomyces cerevisiae
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SCE-6811425] NSF and SNAPs bind cis-SNARE at the ER membrane - Saccharomyces cerevisiae
inferredFrom	[BlackBoxEvent:R-HSA-6811427] COPI vesicle uncoating at the ER - Homo sapiens
input	[Complex:R-SCE-6811379] RAB1:GTP:coatomer:p24 dimers:SEC22B:cargo:NBAS:RINT1:ZW10:STX18:USE1L:BNIP1 [endoplasmic reticulum membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	COPI vesicle uncoating at the ER
output	[Complex:R-SCE-6807805] coatomer [cytosol] [DefinedSet:R-SCE-6814053] Golgi-to-ER cargo [endoplasmic reticulum membrane] [DefinedSet:R-SCE-6811326] p24 dimers [endoplasmic reticulum membrane] [Complex:R-SCE-5694296] RAB1:GDP [cytosol] [Complex:R-SCE-6811343] SEC22B:STX18:USE1L:BNIP1 [endoplasmic reticulum membrane]
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-6811427
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SCE-6811434] COPI-dependent Golgi-to-ER retrograde traffic
(precedingEvent)	[Reaction:R-SCE-6811425] NSF and SNAPs bind cis-SNARE at the ER membrane
(inferredTo)	[BlackBoxEvent:R-HSA-6811427] COPI vesicle uncoating at the ER