Reactome | CD28 dependent Vav1 pathway

Schema > Pathway > Entries

created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11107430
displayName	CD28 dependent Vav1 pathway
eventOf	[Pathway:R-SCE-389356] Co-stimulation by CD28 - Saccharomyces cerevisiae
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-SCE-389788] Activation of PAKs by RAC1 and CDC42 - Saccharomyces cerevisiae
inferredFrom	[Pathway:R-HSA-389359] CD28 dependent Vav1 pathway - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	CD28 dependent Vav1 pathway
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-389359
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SCE-389356] Co-stimulation by CD28
(inferredTo)	[Pathway:R-HSA-389359] CD28 dependent Vav1 pathway

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