Reactome | Insulin processing

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Insulin processing Show undefined attributes

compartment	[Compartment:7660] nucleoplasm [Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane [Compartment:17957] endoplasmic reticulum lumen [Compartment:13959] COPII-coated ER to Golgi transport vesicle [Compartment:17963] Golgi lumen [Compartment:1462052] secretory granule lumen [Compartment:216813] secretory granule membrane [Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11107366
displayName	Insulin processing
eventOf	[Pathway:R-SCE-2980736] Peptide hormone metabolism - Saccharomyces cerevisiae
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:19560] insulin processing
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-SCE-9820566] ZnT5 transports zinc into the golgi apparatus - Saccharomyces cerevisiae [Reaction:R-SCE-437085] ZnT5 transports zinc into secretory granules in pancreatic beta cells - Saccharomyces cerevisiae [BlackBoxEvent:R-SCE-265177] Exocyst complex formation - Saccharomyces cerevisiae
inferredFrom	[Pathway:R-HSA-264876] Insulin processing - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Insulin processing
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-264876
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SCE-2980736] Peptide hormone metabolism
(inferredTo)	[Pathway:R-HSA-264876] Insulin processing