Reactome | EGFR Transactivation by Gastrin

Schema > Pathway > Entries

created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11107454
displayName	EGFR Transactivation by Gastrin
eventOf	[Pathway:R-SCE-881907] Gastrin-CREB signalling pathway via PKC and MAPK - Saccharomyces cerevisiae
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-SCE-400015] Diacylgycerol activates Protein kinase C, alpha type - Saccharomyces cerevisiae
inferredFrom	[Pathway:R-HSA-2179392] EGFR Transactivation by Gastrin - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	EGFR Transactivation by Gastrin
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-2179392
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SCE-881907] Gastrin-CREB signalling pathway via PKC and MAPK
(inferredTo)	[Pathway:R-HSA-2179392] EGFR Transactivation by Gastrin

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