Reactome | Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase

Schema > Reaction > Entries

Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase Show undefined attributes

catalystActivity	[CatalystActivity:11092633] acetate CoA-transferase activity of ACAA1 [peroxisomal matrix]
category	transition
compartment	[Compartment:17951] peroxisomal matrix
created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11092635
displayName	Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase
eventOf	[Pathway:R-SCE-2046106] alpha-linolenic acid (ALA) metabolism - Saccharomyces cerevisiae
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-SCE-2066779] Conversion of DHA-CoA to docosahexaenoic acid (DHA) - Saccharomyces cerevisiae
inferredFrom	[Reaction:R-HSA-2066788] Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase - Homo sapiens
input	[SimpleEntity:R-ALL-2066762] 1-3-oxo-THA-CoA [peroxisomal matrix] [SimpleEntity:R-ALL-193514] CoA-SH [peroxisomal matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase
output	[SimpleEntity:R-ALL-353123] Ac-CoA [peroxisomal matrix] [SimpleEntity:R-ALL-2066765] DHA-CoA [peroxisomal matrix]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-2066788
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SCE-2046106] alpha-linolenic acid (ALA) metabolism
(precedingEvent)	[Reaction:R-SCE-2066779] Conversion of DHA-CoA to docosahexaenoic acid (DHA)
(inferredTo)	[Reaction:R-HSA-2066788] Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase

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