Reactome | Synthesis of bile acids and bile salts via 27-hydroxycholesterol

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Synthesis of bile acids and bile salts via 27-hydroxycholesterol Show undefined attributes

created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11107214
displayName	Synthesis of bile acids and bile salts via 27-hydroxycholesterol
eventOf	[Pathway:R-SCE-192105] Synthesis of bile acids and bile salts - Saccharomyces cerevisiae
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:20533] bile acid biosynthetic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-SCE-193821] 4-cholesten-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-7alpha,12alpha,27-triol-3-one - Saccharomyces cerevisiae [Reaction:R-SCE-193824] 4-cholesten-7alpha,27-diol-3-one is reduced to 5beta-cholestan-7alpha,27-diol-3-one - Saccharomyces cerevisiae [Reaction:R-SCE-193800] 5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol - Saccharomyces cerevisiae [Reaction:R-SCE-193841] 5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol - Saccharomyces cerevisiae
inferredFrom	[Pathway:R-HSA-193807] Synthesis of bile acids and bile salts via 27-hydroxycholesterol - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Synthesis of bile acids and bile salts via 27-hydroxycholesterol
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-193807
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SCE-192105] Synthesis of bile acids and bile salts
(inferredTo)	[Pathway:R-HSA-193807] Synthesis of bile acids and bile salts via 27-hydroxycholesterol

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