Reactome | Estrogen biosynthesis

Schema > Pathway > Entries

created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11107958
displayName	Estrogen biosynthesis
eventOf	[Pathway:R-SCE-196071] Metabolism of steroid hormones - Saccharomyces cerevisiae
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:21394] estrogen biosynthetic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-SCE-5693390] HSD17B11 dehydrogenates EST17b to E1 - Saccharomyces cerevisiae [Reaction:R-SCE-5696822] AKR1B15 reduces EST17b to E1 - Saccharomyces cerevisiae
inferredFrom	[Pathway:R-HSA-193144] Estrogen biosynthesis - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Estrogen biosynthesis
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-193144
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SCE-196071] Metabolism of steroid hormones
(inferredTo)	[Pathway:R-HSA-193144] Estrogen biosynthesis

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