Reactome | 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C

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2-acyl LPC is hydrolyzed to GPCho by PLA2G4C Show undefined attributes

catalystActivity	[CatalystActivity:11091493] phosphatidylcholine lysophospholipase A1 activity of PLA2G4C [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11091581
displayName	2-acyl LPC is hydrolyzed to GPCho by PLA2G4C
eventOf	[Pathway:R-SCE-1483115] Hydrolysis of LPC - Saccharomyces cerevisiae
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-1482629] 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C - Homo sapiens
input	[SimpleEntity:R-ALL-975614] 2-acyl LPC [endoplasmic reticulum membrane] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	2-acyl LPC is hydrolyzed to GPCho by PLA2G4C
output	[SimpleEntity:R-ALL-1498750] GPCho [cytosol] [SimpleEntity:R-ALL-1524021] LCFA(-) [endoplasmic reticulum membrane]
precedingEvent	[Reaction:R-SCE-1482862] PC is hydrolysed to 2-acyl LPC by PLA2[7] - Saccharomyces cerevisiae [Reaction:R-SCE-1482827] PC is hydrolyzed to 2-acyl LPC by PLA2G4C - Saccharomyces cerevisiae
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-1482629
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SCE-1483115] Hydrolysis of LPC
(inferredTo)	[Reaction:R-HSA-1482629] 2-acyl LPC is hydrolyzed to GPCho by PLA2G4C

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