Reactome | TWIK-related alkaline pH activated K+ channel (TALK)

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TWIK-related alkaline pH activated K+ channel (TALK) Show undefined attributes

compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
dbId	11107642
displayName	TWIK-related alkaline pH activated K+ channel (TALK)
eventOf	[Pathway:R-SCE-1296346] Tandem pore domain potassium channels - Saccharomyces cerevisiae
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:1042694] potassium ion transmembrane transport
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-SCE-1299359] Activation of TALK - Saccharomyces cerevisiae
inferredFrom	[Pathway:R-HSA-1299361] TWIK-related alkaline pH activated K+ channel (TALK) - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	TWIK-related alkaline pH activated K+ channel (TALK)
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68322] Saccharomyces cerevisiae
stId	R-SCE-1299361
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SCE-1296346] Tandem pore domain potassium channels
(inferredTo)	[Pathway:R-HSA-1299361] TWIK-related alkaline pH activated K+ channel (TALK)

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