Reactome | Epigenetic regulation by WDR5-containing histone modifying complexes

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Epigenetic regulation by WDR5-containing histone modifying complexes Show undefined attributes

created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10225341
displayName	Epigenetic regulation by WDR5-containing histone modifying complexes
eventOf	[Pathway:R-RNO-212165] Epigenetic regulation of gene expression - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-RNO-9772755] Formation of WDR5-containing histone-modifying complexes - Rattus norvegicus [Pathway:R-RNO-9818564] Epigenetic regulation of gene expression by MLL3 and MLL4 complexes - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-9917777] Epigenetic regulation by WDR5-containing histone modifying complexes - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	5
name	Epigenetic regulation by WDR5-containing histone modifying complexes
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9917777
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-212165] Epigenetic regulation of gene expression
(inferredTo)	[Pathway:R-HSA-9917777] Epigenetic regulation by WDR5-containing histone modifying complexes

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