Reactome | AcK-IDH2 dimer [mitochondrial matrix]

Schema > Complex > Entries

compartment	[Compartment:5460] mitochondrial matrix
consumedByEvent	[Reaction:R-RNO-9854463] SIRT3 deacetylates AcK-IDH2 dimer - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10141960
displayName	AcK-IDH2 dimer [mitochondrial matrix]
hasComponent	2 × [EntityWithAccessionedSequence:R-RNO-5688283] AcK-IDH2 [mitochondrial matrix]
inDisease	false
inferredFrom	[Complex:R-HSA-9854462] AcK-IDH2 dimer [mitochondrial matrix] - Homo sapiens
maxDepth	2
name	AcK-IDH2 dimer
negativelyRegulates	[NegativeRegulation:10141963] Negative regulation by 'AcK-IDH2 dimer [mitochondrial matrix]'
producedByEvent	[Reaction:R-RNO-9854415] ACAT1 tetramer acetylates IDH2 dimer - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9854462
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-RNO-9854463] SIRT3 deacetylates AcK-IDH2 dimer
(output)	[Reaction:R-RNO-9854415] ACAT1 tetramer acetylates IDH2 dimer
(regulator)	[NegativeRegulation:10141963] Negative regulation by 'AcK-IDH2 dimer [mitochondrial matrix]'
(inferredTo)	[Complex:R-HSA-9854462] AcK-IDH2 dimer [mitochondrial matrix]

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