Reactome | K63polyUb-TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane]

Schema > Complex > Entries

compartment	[Compartment:74700] endosome membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10216719
displayName	K63polyUb-TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane]
hasComponent	[Complex:R-RNO-9730427] K63polyUb-K30,K401-TBK1 homodimer [cytosol] [Complex:R-RNO-5362507] K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-9823909] K63polyUb-TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] - Homo sapiens
maxDepth	8
name	K63polyUb-TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14
producedByEvent	[BlackBoxEvent:R-RNO-9823904] TBK1 is ubiquitinated within TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9823909
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[BlackBoxEvent:R-RNO-9823904] TBK1 is ubiquitinated within TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4
(inferredTo)	[Complex:R-HSA-9823909] K63polyUb-TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane]

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