Reactome | p-IRAK2:K63-linked pUb oligo-TRAF6 [endosome membrane]

Schema > Complex > Entries

compartment	[Compartment:74700] endosome membrane
componentOf	[Complex:R-RNO-975099] p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [endosome membrane] - Rattus norvegicus [Complex:R-RNO-975171] p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [endosome membrane] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-975097] Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10141659
displayName	p-IRAK2:K63-linked pUb oligo-TRAF6 [endosome membrane]
hasComponent	[EntityWithAccessionedSequence:R-RNO-975187] phospho-p-IRAK2 [endosome membrane] 3 × [EntityWithAccessionedSequence:R-RNO-450227] Traf6 [endosome membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-975164] p-IRAK2:K63-linked pUb oligo-TRAF6 [endosome membrane] - Homo sapiens
maxDepth	2
memberOf	[DefinedSet:R-RNO-975153] K63-linked polyUb TRAF6 complexes [endosome membrane] - Rattus norvegicus
name	p-IRAK2:K63-linked pUb oligo-TRAF6
producedByEvent	[BlackBoxEvent:R-RNO-975147] Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 at endosome membrane - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-975164
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-RNO-975097] Activated TRAF6:p-IRAK2 interacts with TAK1 complex upon TLR7/8 or 9 stimulation
(hasComponent)	[Complex:R-RNO-975171] p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [endosome membrane] [Complex:R-RNO-975099] p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [endosome membrane]
(output)	[BlackBoxEvent:R-RNO-975147] Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 at endosome membrane
(hasMember)	[DefinedSet:R-RNO-975153] K63-linked polyUb TRAF6 complexes [endosome membrane]
(inferredTo)	[Complex:R-HSA-975164] p-IRAK2:K63-linked pUb oligo-TRAF6 [endosome membrane]