Reactome | SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes

Schema > Reaction > Entries

SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes Show undefined attributes

catalystActivity	[CatalystActivity:10143508] secondary active transmembrane transporter activity of OAT2/4 [plasma membrane]
category	transition
compartment	[Compartment:984] extracellular region [Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10214876
displayName	SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes
eventOf	[Pathway:R-RNO-9749641] Aspirin ADME - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-2314678] ASA- acetylates PTGS1 - Rattus norvegicus [Reaction:R-RNO-2314686] ASA- acetylates PTGS2 - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-9749583] SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes - Homo sapiens
input	[DefinedSet:R-ALL-9749786] ASA-, ST [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes SLC22A7 transports ASA-,ST into liver cells
output	[DefinedSet:R-ALL-9749576] ASA-, ST (hepatocyte) [cytosol]
precedingEvent	[Reaction:R-RNO-9749609] BCHE hydrolyzes ASA- - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9749583
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-9749641] Aspirin ADME
(precedingEvent)	[Reaction:R-RNO-2314678] ASA- acetylates PTGS1 [Reaction:R-RNO-2314686] ASA- acetylates PTGS2
(inferredTo)	[Reaction:R-HSA-9749583] SLC22A7 transports ASA-,ST from extracellular region to cytosol of hepatocytes

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