Reactome | ORC1 binds to H4K20me2

Schema > Reaction > Entries

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10214854
displayName	ORC1 binds to H4K20me2
eventOf	[Pathway:R-RNO-68616] Assembly of the ORC complex at the origin of replication - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9749197] ORC1 binds to H4K20me2 - Homo sapiens
input	[Complex:R-RNO-9749196] H4K20Me2-nucleosome [nucleoplasm] [EntityWithAccessionedSequence:R-RNO-68522] ORC1 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	ORC1 binds to H4K20me2
output	[Complex:R-RNO-9749192] ORC1:H4K20Me2-nucleosome [nucleoplasm]
precedingEvent	[BlackBoxEvent:R-RNO-9734730] ORC1 translocates to the nucleus - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9749197
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-68616] Assembly of the ORC complex at the origin of replication
(inferredTo)	[Reaction:R-HSA-9749197] ORC1 binds to H4K20me2