Reactome | EDNRA binds selective ERAs

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10214696
displayName	EDNRA binds selective ERAs
eventOf	[Pathway:R-RNO-375276] Peptide ligand-binding receptors - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9731931] EDNRA binds selective ERAs - Homo sapiens
input	[EntityWithAccessionedSequence:R-RNO-388549] Ednra [plasma membrane] [DefinedSet:R-ALL-9731926] selective ERAs [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	EDNRA binds selective ERAs EDNRA binds selective EDNR antagonists
output	[Complex:R-RNO-9731927] EDNRA:selective ERAs [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9731931
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-375276] Peptide ligand-binding receptors
(inferredTo)	[Reaction:R-HSA-9731931] EDNRA binds selective ERAs

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