Reactome | CO binds to Cytochrome c oxidase

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70616] mitochondrial inner membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10213758
displayName	CO binds to Cytochrome c oxidase
eventOf	[Pathway:R-RNO-9707564] Cytoprotection by HMOX1 - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9709406] CO binds to Cytochrome c oxidase - Homo sapiens
input	[SimpleEntity:R-ALL-9709326] CO [mitochondrial inner membrane] [Complex:R-RNO-164316] Cytochrome c oxidase [mitochondrial inner membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	CO binds to Cytochrome c oxidase
output	[Complex:R-RNO-9709412] Cytochrome c oxidase:CO [mitochondrial inner membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9709406
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-9707564] Cytoprotection by HMOX1
(inferredTo)	[Reaction:R-HSA-9709406] CO binds to Cytochrome c oxidase

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