Reactome | CASR binds CASR agonists

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10213463
displayName	CASR binds CASR agonists
eventOf	[Pathway:R-RNO-420499] Class C/3 (Metabotropic glutamate/pheromone receptors) - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9703895] CASR binds CASR agonists - Homo sapiens
input	[EntityWithAccessionedSequence:R-RNO-420719] CASR [plasma membrane] [DefinedSet:R-ALL-9703850] CASR agonists [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	CASR binds CASR agonists
output	[Complex:R-RNO-9703908] CASR:CASR agonists [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9703895
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-420499] Class C/3 (Metabotropic glutamate/pheromone receptors)
(inferredTo)	[Reaction:R-HSA-9703895] CASR binds CASR agonists