Reactome | p-S-RIPK1:p-S199,227-RIPK3:p-T357,S358-MLKL oligomer:PDCD6IP:SDCBP [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10178918
displayName	p-S-RIPK1:p-S199,227-RIPK3:p-T357,S358-MLKL oligomer:PDCD6IP:SDCBP [cytosol]
hasComponent	[Complex:R-RNO-5357794] p-S-RIPK1:p-S199,227-RIPK3:p-T357,S358-MLKL oligomer [cytosol] [EntityWithAccessionedSequence:R-RNO-917717] Pdcd6ip [cytosol] [EntityWithAccessionedSequence:R-RNO-373639] SDCBP [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-9688894] p-S-RIPK1:p-S199,227-RIPK3:p-T357,S358-MLKL oligomer:PDCD6IP:SDCBP [cytosol] - Homo sapiens
maxDepth	5
name	p-S-RIPK1:p-S199,227-RIPK3:p-T357,S358-MLKL oligomer:PDCD6IP:SDCBP
negativelyRegulates	[NegativeRegulation:10178922] Negative regulation by 'p-S-RIPK1:p-S199,227-RIPK3:p-T357,S358-MLKL oligomer:PDCD6IP:SDCBP [cytosol]'
producedByEvent	[Reaction:R-RNO-9688832] MLKL binds PDCD6IP and SDCBP - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9688894
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[Reaction:R-RNO-9688832] MLKL binds PDCD6IP and SDCBP
(regulator)	[NegativeRegulation:10178922] Negative regulation by 'p-S-RIPK1:p-S199,227-RIPK3:p-T357,S358-MLKL oligomer:PDCD6IP:SDCBP [cytosol]'
(inferredTo)	[Complex:R-HSA-9688894] p-S-RIPK1:p-S199,227-RIPK3:p-T357,S358-MLKL oligomer:PDCD6IP:SDCBP [cytosol]

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