Reactome | IL1R1 binds IL1R1 inhibitors

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10212905
displayName	IL1R1 binds IL1R1 inhibitors
eventOf	[Pathway:R-RNO-9020702] Interleukin-1 signaling - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9681763] IL1R1 binds IL1R1 inhibitors - Homo sapiens
input	[EntityWithAccessionedSequence:R-RNO-197595] Il1r1 [plasma membrane] [DefinedSet:R-ALL-9681804] IL1R1 inhibitors [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	IL1R1 binds IL1R1 inhibitors
output	[Complex:R-RNO-9681780] IL1R1:IL1R1 inhibitors [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9681763
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-9020702] Interleukin-1 signaling
(inferredTo)	[Reaction:R-HSA-9681763] IL1R1 binds IL1R1 inhibitors

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