Reactome | PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1

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PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1 Show undefined attributes

category	dissociation
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10211894
displayName	PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1
eventOf	[Pathway:R-RNO-9646399] Aggrephagy - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9641109] PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1 - Homo sapiens
input	[Complex:R-RNO-9641113] PolyUb:Misfolded proteins:PRKN:UBE2N:UBE2V1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1
output	[DefinedSet:R-RNO-9641120] PolyUb-Misfolded Proteins [cytosol] [Complex:R-RNO-9641124] UBE2N:UBE2V1:PRKN [cytosol]
precedingEvent	[Polymerisation:R-RNO-9641127] Ub:misfolded proteins polymerize to PolyUb:misfolded proteins - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9641109
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-9646399] Aggrephagy
(inferredTo)	[Reaction:R-HSA-9641109] PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1

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