Reactome | GPER1 signaling

Schema > Pathway > Entries

created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10222497
displayName	GPER1 signaling
eventOf	[Pathway:R-RNO-418555] G alpha (s) signalling events - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-RNO-9624017] p-SHC1 binds integrin alpha5beta1:fibronectin - Rattus norvegicus [Reaction:R-RNO-8951727] cAMP binds PKA tetramer - Rattus norvegicus [Reaction:R-RNO-111925] cAMP induces dissociation of inactive PKA tetramers - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-9634597] GPER1 signaling - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	GPER1 signaling
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9634597
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-418555] G alpha (s) signalling events
(inferredTo)	[Pathway:R-HSA-9634597] GPER1 signaling