Reactome | Activation of RAC1 downstream of NMDARs

Schema > Pathway > Entries

created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10225301
displayName	Activation of RAC1 downstream of NMDARs
eventOf	[Pathway:R-RNO-438064] Post NMDA receptor activation events - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:645] chemical synaptic transmission
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-RNO-9619355] CaMKK autophosphorylates in the cytosol - Rattus norvegicus [Reaction:R-RNO-9619376] CAMK1 binds calmodulin - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-9619229] Activation of RAC1 downstream of NMDARs - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Activation of RAC1 downstream of NMDARs
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9619229
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-438064] Post NMDA receptor activation events
(inferredTo)	[Pathway:R-HSA-9619229] Activation of RAC1 downstream of NMDARs

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