Reactome | p-IRAK2:K63-linked pUb oligo-TRAF6 [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10146183] ubiquitin-protein transferase activity of p-IRAK2:K63-linked pUb oligo-TRAF6 [plasma membrane]
compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-RNO-936953] p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane] - Rattus norvegicus [Complex:R-RNO-937008] p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [plasma membrane] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-936960] Activated TRAF6:p-IRAK2 interacts with TAK1 complex - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10146158
displayName	p-IRAK2:K63-linked pUb oligo-TRAF6 [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-RNO-936949] phospho-p-IRAK2 [plasma membrane] 3 × [EntityWithAccessionedSequence:R-RNO-936980] Traf6 [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-936988] p-IRAK2:K63-linked pUb oligo-TRAF6 [plasma membrane] - Homo sapiens
maxDepth	2
name	p-IRAK2:K63-linked pUb oligo-TRAF6
producedByEvent	[BlackBoxEvent:R-RNO-936942] Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2 - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-936988
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-RNO-936960] Activated TRAF6:p-IRAK2 interacts with TAK1 complex
(physicalEntity)	[CatalystActivity:10146183] ubiquitin-protein transferase activity of p-IRAK2:K63-linked pUb oligo-TRAF6 [plasma membrane]
(output)	[BlackBoxEvent:R-RNO-936942] Auto ubiquitination of oligo-TRAF6 bound to p-IRAK2
(hasComponent)	[Complex:R-RNO-937008] p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [plasma membrane] [Complex:R-RNO-936953] p-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complex [plasma membrane]
(inferredTo)	[Complex:R-HSA-936988] p-IRAK2:K63-linked pUb oligo-TRAF6 [plasma membrane]