Reactome | Biosynthesis of electrophilic ?-3 PUFA oxo-derivatives

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Biosynthesis of electrophilic ?-3 PUFA oxo-derivatives Show undefined attributes

created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10225243
displayName	Biosynthesis of electrophilic ?-3 PUFA oxo-derivatives
eventOf	[Pathway:R-RNO-9018678] Biosynthesis of specialized proresolving mediators (SPMs) - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:81415] long-chain fatty acid biosynthetic process
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-RNO-9027532] PTGS2 dimer oxidises DHA to 13-HDHA - Rattus norvegicus [Reaction:R-RNO-9027627] Ac-PTGS2 dimer oxidises DHA to 17-HDHA (macrophages) - Rattus norvegicus [Reaction:R-RNO-9027624] ALOX5 oxidises DHA to 7-HDHA - Rattus norvegicus [Reaction:R-RNO-9027607] Ac-PTGS2 dimer oxidises DPAn-3 to 17-HDPAn-3 - Rattus norvegicus [Reaction:R-RNO-9027633] ALOX5 oxidises DPAn-3 to 7-HDPAn-3 - Rattus norvegicus [Reaction:R-RNO-9027628] ALOX5 oxidises EPA to 5-HEPE - Rattus norvegicus [Reaction:R-RNO-9028255] PTGS2 dimer oxidises EPA to PGH3 - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-9027604] Biosynthesis of electrophilic ?-3 PUFA oxo-derivatives - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Biosynthesis of electrophilic ?-3 PUFA oxo-derivatives
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9027604
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-9018678] Biosynthesis of specialized proresolving mediators (SPMs)
(inferredTo)	[Pathway:R-HSA-9027604] Biosynthesis of electrophilic ?-3 PUFA oxo-derivatives

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