Reactome | VKORC1 inhibitors binds VKORC1 dimer

Schema > Reaction > Entries

category	binding
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10210020
displayName	VKORC1 inhibitors binds VKORC1 dimer
eventOf	[Pathway:R-RNO-6806664] Metabolism of vitamin K - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9026967] VKORC1 inhibitors binds VKORC1 dimer - Homo sapiens
input	[Complex:R-RNO-6806371] VKORC1 dimer [endoplasmic reticulum membrane] [DefinedSet:R-HSA-9035082] VKORC1 inhibitors [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	VKORC1 inhibitors binds VKORC1 dimer
output	[Complex:R-RNO-9035037] VKORC1 inhibitors:VKORC1 dimer [endoplasmic reticulum membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9026967
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-6806664] Metabolism of vitamin K
(inferredTo)	[Reaction:R-HSA-9026967] VKORC1 inhibitors binds VKORC1 dimer

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