Reactome | ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3

Schema > Reaction > Entries

ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 Show undefined attributes

catalystActivity	[CatalystActivity:10209671] arachidonate 15-lipoxygenase activity of ALOX15 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10209991
displayName	ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3
eventOf	[Pathway:R-RNO-9026286] Biosynthesis of DPAn-3-derived protectins and resolvins - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-9025999] ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 - Rattus norvegicus [Reaction:R-RNO-9025996] ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3 - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-9026003] ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3 - Homo sapiens
input	[SimpleEntity:R-ALL-9608444] DPAn-3 [cytosol] [SimpleEntity:R-ALL-29368] O2 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3
output	[SimpleEntity:R-ALL-9026047] 17(S)-Hp-DPAn-3 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9026003
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-9026286] Biosynthesis of DPAn-3-derived protectins and resolvins
(precedingEvent)	[Reaction:R-RNO-9025999] ALOX5 dehydrogenates 17(S)-Hp-DPAn-3 to 16(S),17(S)-epoxy-DPAn-3 [Reaction:R-RNO-9025996] ALOX5 oxidises 17(S)-Hp-DPAn-3 to 7,17-diHp-DPAn-3
(inferredTo)	[Reaction:R-HSA-9026003] ALOX15 oxidises DPAn-3 to 17(S)-Hp-DPAn-3

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