Reactome | ATG12 forms a thioester bond with ATG7 dimer

Schema > Reaction > Entries

category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10209722
displayName	ATG12 forms a thioester bond with ATG7 dimer
eventOf	[Pathway:R-RNO-1632852] Macroautophagy - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9020616] ATG12 forms a thioester bond with ATG7 dimer - Homo sapiens
input	[Complex:R-RNO-9020617] ATG12:ATG7 dimer [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	ATG12 forms a thioester bond with ATG7 dimer
output	[Complex:R-RNO-5682668] ATG12:ATG7:CysO572-ATG7 [cytosol]
precedingEvent	[Reaction:R-RNO-5681980] ATG12 binds ATG7 dimer - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-9020616
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-1632852] Macroautophagy
(inferredTo)	[Reaction:R-HSA-9020616] ATG12 forms a thioester bond with ATG7 dimer

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